PartsTable
Technical Data Sheet
PartsTable / STORAGE_HDD / P06388-B21
P06388-B21 ✓ Verified by PartsTable
HPE · STORAGE_HDD · 3.5_SATA_HDD
WHAT YOU NEED TO KNOW
SAS backplane supports SATA, not vice versa NL-SAS = SAS protocol at nearline (7.2K) speed — NOT SATA
Gen8 LFF tray ≠ Gen10 tray — different screw holes
PRODUCT OVERVIEW

HPE | Disk-HDD 4TB 7,2K SATA 3,5" SC DS. Available through authorized enterprise resellers and TPM (Third Party Maintenance) channels. Verify compatibility with your specific system configuration before ordering.

WHERE IT FITS
STORAGE_HDD→ 3.5_SATA_HDD→ P06388-B21
SPECIFICATIONS
Part NumberP06388-B21
ManufacturerHPE
Capacity4TB
COMPONENT DIAGRAM
RELEASE LATCH 4TB NL-SAS 7.2K P06388-B21 HPE NL-SAS INTERFACE INTERPOSER SAS drive in SATA tray? Check board compatibility 3.5" (101.6 x 146mm) LFF 3.5" DRIVE | 4TB | NL-SAS 7.2K NL-SAS uses SAS protocol at 7.2K RPM | SAS backplane supports SATA, not reverse Tray generation matters | Gen8 LFF tray differs from Gen10 TITLE LFF 3.5" DRIVE PN P06388-B21 MFR HPE
KEY FEATURES
•
4TB Capacity
TYPICAL APPLICATIONS
  • Enterprise storage arrays and SANs
  • Direct-attached storage (DAS) expansion
  • Database tier storage (OLTP, OLAP)
  • Virtual machine datastore expansion
  • Backup-to-disk and disaster recovery targets
  • Content delivery and media streaming storage
VERIFIED SUBSTITUTES & CROSS-REFERENCES 12
872491-K21Compatible
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
compatible
872491-B21Compatible
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
compatible
872772-001Compatible
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
compatible
846522-004Compatible
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF HDD - Bare Drive
compatible
872293-002Compatible
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF HDD - Bare Drive
compatible
872295-002Compatible
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF HDD - Bare Drive
compatible
LIFECYCLE
StatusUNKNOWN
Availability—
RoHS CompliantEAR99ESD SensitiveNot HAZMAT
THIS PART SUBSTITUTES FOR 19
879481-001SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
MB004000GWFVUSUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
MB004000GWFWBSUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
MB004000GWKGVSUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
MB4000GVYZKSUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
P03714-B21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
P03750-001SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
P06464-001SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
846522-004SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
861683-B21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
861683-H21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
861683-K21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
861683-X21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
862133-001SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
872293-002SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
872295-002SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
872491-B21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
872491-K21SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
872772-001SUBSTITUTE
HP 4Tb SATA 6G 7.2K 512n Digitally Signed MDL LFF SC HDD
HPE
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FREQUENTLY ASKED QUESTIONS
What is P06388-B21?
P06388-B21 is a HPE | Disk-HDD 4TB 7,2K SATA 3,5" SC DS manufactured by HPE. It is classified as a STORAGE_HDD (3.5_SATA_HDD).
What parts can replace P06388-B21?
There are 12 known substitutes for P06388-B21: 872491-K21, 872491-B21, 872772-001 and 9 more. Substitute compatibility should be verified for your specific system.
Is P06388-B21 still available?
P06388-B21 is currently Unknown.
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✓ Validated with multiple authoritative sources, including Government, OEM, and Certified sources.
PartsTable Design LLC · partstable.com
Last verified: July 2026