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622643-001 — HP 350GB SATA 5400RPM internal hard drive 320 GB 2.5" Serial ATA

HPE · DRIVE SFF
PRODUCT OVERVIEW

622643-001: HP 350GB SATA 5400RPM internal hard drive 320 GB 2.5" Serial ATA.

- As part of its commitment to hardware, software, and solution innovation, HP is proud to introduce this breakthrough platform configuration stability to HP Workstation customers. HP Stable & Consistent Offerings are built on the foundation of a carefully chosen set of hardware and software designed and tested to work with all HP Workstation platforms through their end of life. Available through authorized enterprise resellers and TPM (Third Party Maintenance) channels.

Verify compatibility with your specific system configuration before ordering.

WHERE IT FITS
SFF BAY→ 622643-001
SPECIFICATIONS
Part Number622643-001
ManufacturerHPE
Form FactorSFF
Capacity350GB
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COMPONENT DIAGRAM
LATCH 350GB SAS — 622643-001 SAS CONN WITH TRAY — HOT-PLUG READY Tray: See server gen 350GB SAS — 622643-001 BARE DRIVE — NO LATCH Needs caddy/tray to install 2.5" (70 x 100mm) SFF 2.5" DRIVE | 350GB | SAS — Always ask: "Does it come with tray/caddy?" | Tray PN varies by server generation TITLE SFF 2.5" DRIVE PN 622643-001 CAP 350GB SAS
KEY FEATURES
•
SFF Form Factor
•
350GB Capacity
TYPICAL APPLICATIONS
  • Enterprise storage arrays and SANs
  • Direct-attached storage (DAS) expansion
  • Database tier storage (OLTP, OLAP)
  • Virtual machine datastore expansion
  • Backup-to-disk and disaster recovery targets
  • Content delivery and media streaming storage
SUBSTITUTES & CROSS-REFERENCES 12
462355-002CompatiblePARTNER
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
compatible
463643-002CompatiblePARTNER
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
compatible
463643-003CompatiblePARTNER
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
compatible
465897-001CompatiblePARTNER
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
compatible
465899-001CompatiblePARTNER
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
compatible
465899-002CompatiblePARTNER
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
compatible
LIFECYCLE

No lifecycle data available.

THIS PART SUBSTITUTES FOR 20
459956-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
462355-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
462355-002SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
463643-002SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
463643-003SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
465897-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
465899-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
465899-002SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
465899-003SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
469003-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
480456-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
480605-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
488446-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
488599-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
488599-002SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
489821-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
493199-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
493966-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
496726-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
498310-001SUBSTITUTE
HP 320Gb SATA 3G 5.4K SFF 9.5mm HDD for Laptops
HPE
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FREQUENTLY ASKED QUESTIONS
What is 622643-001?
622643-001 is a HP 350GB SATA 5400RPM internal hard drive 320 GB 2.5" Serial ATA manufactured by HPE.
What parts can replace 622643-001?
There are 12 known substitutes for 622643-001: 462355-002, 463643-002, 463643-003 and 9 more. Substitute compatibility should be verified for your specific system.
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PartsTable commercial catalog: edition Unified commercial catalog snapshot through 2026-09-28, edition date not on file, retrieved 2026-09-28.