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Technical Data Sheet
PartsTable / STORAGE_HDD / 516816-B21
516816-B21 ✓ Verified by PartsTable
HP · STORAGE_HDD · 3.5_SAS_HDD
WHAT YOU NEED TO KNOW
SAS backplane supports SATA, not vice versa NL-SAS = SAS protocol at nearline (7.2K) speed — NOT SATA
Gen8 LFF tray ≠ Gen10 tray — different screw holes
PRODUCT OVERVIEW
HP 450GB 15K 6G 3.5INCH DP ENTERPRISE SAS HDD

A Hypertec equivalent HP 450GB 6G SAS 15K LFF (3.5-inch) Dual Port Enterprise. Key specifications include Capacity: 480GB, Hot-Plug: Yes, Interface: SAS 12Gbps, Drive Type: SSD, Form Factor: 2.5-inch. Available through authorized enterprise resellers and TPM (Third Party Maintenance) channels.

Verify compatibility with your specific system configuration before ordering.

WHERE IT FITS
STORAGE_HDD→ 3.5_SAS_HDD→ 516816-B21
SPECIFICATIONS
Capacity480GB
Hot-PlugYes
InterfaceSAS 12Gbps
Drive TypeSSD
Form Factor2.5-inch
COMPONENT DIAGRAM
RELEASE LATCH 450GB NL-SAS 15K RPM 516816-B21 HP NL-SAS INTERFACE INTERPOSER SAS drive in SATA tray? Check board compatibility 3.5" (101.6 x 146mm) LFF 3.5" DRIVE | 450GB | NL-SAS 15K RPM NL-SAS uses SAS protocol at 7.2K RPM | SAS backplane supports SATA, not reverse Tray generation matters | Gen8 LFF tray differs from Gen10 TITLE LFF 3.5" DRIVE PN 516816-B21 MFR HP
KEY FEATURES
•
450GB Capacity
•
15K RPM Speed
TYPICAL APPLICATIONS
  • Enterprise storage arrays and SANs
  • Direct-attached storage (DAS) expansion
  • Database tier storage (OLTP, OLAP)
  • Virtual machine datastore expansion
  • Backup-to-disk and disaster recovery targets
  • Content delivery and media streaming storage
VERIFIED SUBSTITUTES & CROSS-REFERENCES 12
868221-001Compatible
HP 450GB SAS 6G 15k LFF St HDD
compatible
375874-017Compatible
HP 450Gb SAS 6G 15K LFF HDD - Bare Drive
compatible
375874-018Compatible
HP 450Gb SAS 6G 15K LFF HDD - Bare Drive
compatible
516810-002Compatible
HP 450Gb SAS 6G 15K LFF HDD - Bare Drive
compatible
516832-003Compatible
HP 450Gb SAS 6G 15K LFF HDD - Bare Drive
compatible
516832-004Compatible
HP 450Gb SAS 6G 15K LFF HDD - Bare Drive
compatible
LIFECYCLE
StatusUNKNOWN
Availability—
RoHS CompliantEAR99ESD SensitiveNot HAZMAT
THIS PART SUBSTITUTES FOR 14
EF0450FARMVSUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
EF0450FATFESUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
LU968AASUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
375874-017SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
375874-018SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
516810-002SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
516832-003SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
516832-004SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
517352-001SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
533871-002SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
581313-001SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
623390-001SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
652617-001SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
868221-001SUBSTITUTE
HP 450Gb SAS 6G 15K LFF ST HDD
HPE
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FREQUENTLY ASKED QUESTIONS
What is 516816-B21?
516816-B21 is a HP 450GB 15k 6G 3.5inch DP Enterprise SAS HDD manufactured by HP. It is classified as a STORAGE_HDD (3.5_SAS_HDD).
What parts can replace 516816-B21?
There are 12 known substitutes for 516816-B21: 868221-001, 375874-017, 375874-018 and 9 more. Substitute compatibility should be verified for your specific system.
Is 516816-B21 still available?
516816-B21 is currently Unknown.
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✓ Validated with multiple authoritative sources, including Government, OEM, and Certified sources.
PartsTable Design LLC · partstable.com
Last verified: July 2026