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416127-B21 — Storage Datasheet

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HPE · DRIVE LFF
WHAT YOU NEED TO KNOW
SAS backplane supports SATA, not vice versa NL-SAS = SAS protocol at nearline (7.2K) speed — NOT SATA
Gen8 LFF tray ≠ Gen10 tray — different screw holes
PRODUCT OVERVIEW

Serial Attached SCSI is the logical evolution of SCSI, including its long-established software advantage and the Serial ATA electrical and physical connection interface. SAS meets all these demands while providing the highest performance. Available through authorized enterprise resellers and TPM (Third Party Maintenance) channels.

Verify compatibility with your specific system configuration before ordering.

WHERE IT FITS
LFF BAY→ 416127-B21
SPECIFICATIONS
Part Number416127-B21
ManufacturerHPE
Form FactorLFF
Capacity300GB
Speed15K RPM
COMPONENT DIAGRAM
RELEASE LATCH 300GB NL-SAS 15K RPM 416127-B21 HPE NL-SAS INTERFACE INTERPOSER SAS drive in SATA tray? Check board compatibility 3.5" (101.6 x 146mm) LFF 3.5" DRIVE | 300GB | NL-SAS 15K RPM NL-SAS uses SAS protocol at 7.2K RPM | SAS backplane supports SATA, not reverse Tray generation matters | Gen8 LFF tray differs from Gen10 TITLE LFF 3.5" DRIVE PN 416127-B21 MFR HPE
KEY FEATURES
•
LFF Form Factor
•
300GB Capacity
•
15K RPM Speed
TYPICAL APPLICATIONS
  • Enterprise storage arrays and SANs
  • Direct-attached storage (DAS) expansion
  • Database tier storage (OLTP, OLAP)
  • Virtual machine datastore expansion
  • Backup-to-disk and disaster recovery targets
  • Content delivery and media streaming storage
VERIFIED SUBSTITUTES & CROSS-REFERENCES 12
375874-013Compatible
HP 300GB SAS 3G 15k LFF DP St HDD
compatible
375874-014Compatible
HP 300GB SAS 3G 15k LFF DP St HDD
compatible
375874-015Compatible
HP 300GB SAS 3G 15k LFF DP St HDD
compatible
375874-016Compatible
HP 300GB SAS 3G 15k LFF DP St HDD
compatible
375874-024Compatible
HP 300GB SAS 3G 15k LFF DP St HDD
compatible
417190-004Compatible
HP 300GB SAS 3G 15k LFF DP St HDD
compatible
LIFECYCLE
StatusUNKNOWN
Availability—
RoHS CompliantEAR99ESD SensitiveNot HAZMAT
THIS PART SUBSTITUTES FOR 20
DF0300B8053SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
DF0300BAERFSUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
DF300A4950SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
DF300BABUFSUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
DF300BAERFSUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
DF300BAFDVSUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
DF300BB6C3SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
RH937AASUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
375874-013SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
375874-014SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
375874-015SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
375874-016SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
375874-024SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
416248-001SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
417190-004SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
434108-001SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
434611-001SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
436936-001SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
443169-003SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
454228-002SUBSTITUTE
HP 300Gb SAS 3G 15K LFF DP ST HDD
HPE
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FREQUENTLY ASKED QUESTIONS
What is 416127-B21?
416127-B21 is a HP 300GB 3G SAS 15K LFF (3.5-inch) Dual Port Enterprise 3yr Warranty Hard Drive internal hard drive manufactured by HPE.
What parts can replace 416127-B21?
There are 12 known substitutes for 416127-B21: 375874-013, 375874-014, 375874-015 and 9 more. Substitute compatibility should be verified for your specific system.
Is 416127-B21 still available?
416127-B21 is currently Unknown.
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PartsTable Design LLC · partstable.com
Last verified: September 2026